The Importance of 6-Aminohexanoic Acid as a Hydrophobic,Flexible Structural Element |
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Authors: | Agnieszka Markowska Adam Roman Markowski Iwona Jarocka-Karpowicz |
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Affiliation: | 1.Department of Analytical Chemistry, Medical University of Bialystok, 15-089 Bialystok, Poland;2.Department of Internal Medicine and Gastroenterology, Polish Red Cross Memorial Municipal Hospital, 79 Henryk Sienkiewicz Street, 15-003 Bialystok, Poland; |
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Abstract: | 6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules. |
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Keywords: | 6-aminohexanoic acid antifibrynolytics linker |
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