海洋鱼源抗菌肽的研究进展及其在食品安全中的应用前景

抗生素过度使用所导致日益严重的耐药性威胁已成为制约食品工业可持续发展的障碍，而海洋鱼类中存在具有广谱抗微生物活性的抗菌肽，其或将成为最佳的新型“抗生素替代物”。因此，从海洋鱼类中发现更多活性丰富的抗菌肽，并探索其在食品安全领域应用的相关研究成为热点。本文综述了海洋鱼源抗菌肽的结构、生物活性及作用机制的研究进展，并展望了其在食品安全领域的应用前景，以期为海洋鱼源抗菌肽的研究利用提供依据。

A Review of Antimicrobial Peptides from Marine Fish and Its Potential Application in Food Safety

The sustainable development of the food industry is hindered by the threat of drug resistance, which is caused by the overuse of antibiotics. Fortunately, marine fish-derived antimicrobial peptides with broad-spectrum activity are considered to be the best new antibiotic substitutes in the future. Therefore, discovering more antimicrobial peptides from marine fish and exploring its application in the field of food safety have become a hot research topic. This paper reviews recent progress in understanding the structure, biological activity and mechanism of action of antimicrobial peptides derived from marine fish, and it discusses future prospects for the application of the antimicrobial peptides in food safety. This paper is expected to provide evidence rationale for the research and utilization of antimicrobial peptides derived from marine fish.