微波诱发工作人员外周血淋巴细胞亚群变化情况调查

对某研究所微波接触人员（接触组）和非微波作业人员（对照组）进行调查，调查指标为外周血白细胞数和淋巴细胞百分率，以及T淋巴细胞亚群CD3＋、CD4＋、CD8＋比例和CD4＋／CD8＋比值，探索长期低剂量高功率微波辐射对工作人员免疫功能的影响。结果表明：与对照组相比，接触组白细胞数和淋巴细胞百分比均降低，但差异不显著；接触组CD3＋、CD4＋、CD8＋比例均升高，CD4＋／CD8＋比值降低，差异显著；接触组≤10a组的T细胞亚群的变化差异不显著，接触组〉10a组CD3＋、CD4＋、CD8＋比例及CD4＋／CD8＋比值均升高，且CD3＋比例升高差异显著；接触组和对照组组内工龄≤10a和）10a间T淋巴细胞亚群的差异不显著。结果提示，低剂量高功率微波辐射能明显导致人体免疫功能紊乱，但未表现出累积效应。客观有效的职业防护应当引起关注。

Effects of Microwave Radiation on T Lymphocytes of Workers

To investigate the effects of long-term, low-dose and high-power microwave radiation on immuno-logic function of workers. The changes of peripheral blood leukocytes, lymphocyte percentage, and CD3＋ , CD4＋ , CD8＋ T cells and ratios of CD4＋/CD8＋ were determined in 38 microwave radiation-exposed workers （exposed group） and 39 non-microwave radiation-exposed workers （control group）. Compared with the control group, peripheral blood leukocytes and lymphocyte percentage were decreased in the exposed group, but the difference was not significant. CD3＋, CD4＋ , CD8＋ cells were increased significantly and ratio of CD4＋/ CD8＋ was diminished significantly in the exposed group. In the exposed group, T cell subsets in ≤ 10 years service length group was not significant as compared with the control group. But CD3＋, CD4＋ , CD8＋ cells and ratio of CD4＋/CD8＋ were increased in 〉 10 years service length group of the exposed group, and CD3＋ cells were increased significantly. Inaddition, 2 service length groups within the exposed group and control group, CD3＋, CD4＋ , CD8＋ T ceils and ratio of CD4＋/CD8＋ were not significant. The Long-term, low-dosage and high-power microwave radiation can cause significant immune dysfunction to the exposed workers, but without cumulative effects. Effective occupational protection should be adopted.