食品接触材料中非有意添加物的检测方法

食品接触材料中的非有意添加物(non-intentionally added substance, NIAS)作为影响食品安全的重要因素而日益受到关注。对NIAS的化合物种类鉴定和含量测定是对食品接触材料进行安全评估和监管的前提条件。目前, 主流的分析策略是依据待测NIAS的挥发特性, 分别选择气相色谱(gas chromatography, GC)或高效液相色谱(high performance liquid chromatography, HPLC)进行分离和定量, 利用质谱(mass spectrometry, MS)谱图特征和色谱出峰时间(retention time, RT), 借助质谱数据库对NIAS进行定性。与欧洲国家相比, 我国在NIAS分析检测领域起步较晚, 亟需补强食品接触材料NIAS物质数据库和物质鉴定领域的研究基础。下一步建议加强化学结构分析的基础研究, 培养食品接触材料中NIAS鉴定人才团队, 构建食品接触材料中IAS和NIAS物质的信息数据库, 最终提高食品接触材料NIAS检测技术水平。

Analytical methods of non-intentional added substance in food contact material

The non-intentionally added substance (NIAS) in food contact material is receiving growing concern as an important food safety factor. The identification and determination of NIAS is the prerequisite for the safety assessment and supervision of food contact materials. Currently, the mainstream analysis strategy is using gas chromatography (GC) and high-performance liquid chromatography (HPLC) to separate and quantify the volatile, semi-volatile, and non-volatile NIAS respectively, further identify NIAS by comparing the mass spectrometry (MS) spectral fingerprints and chromatographic retention time with MS libraries. Comparing with European countries, China is relatively late to start its NIAS analysis research, still lack of the experience of identification, and do not have a sufficient database. In order to improve our NIAS identification and determination capability, we should strengthen our basic research on chemical structure analysis, cultivate the talent team in NIAS identification, and establish the database of migration compounds in food contact materials.