螺螨酯类似物AC-101的合成与杀螨活性

为寻求高活性的杀螨剂,通过对螺螨酯进行结构改造,合成了新杀螨活性化合物3-(2,4-二氯苯基)-2-氧-1-氧杂螺[4.5]癸-3-烯-4-基-丁基-1-磺酸酯(试验代号:AC-101;暂命名:螺螨丁酯),并开发了24%悬浮剂(SC)和24%可分散油悬浮剂(OD)制剂。室内生物活性测试显示:在1 mg/L质量浓度下,螺螨丁酯对朱砂叶螨螨卵的防效达95%。田间药效试验显示:24%螺螨丁酯SC和OD药后14 d对山楂叶螨的最高防效分别为95.7%和96.2%,药后21 d对山楂叶螨的防效在73.6%以上。螺螨丁酯具有杀螨活性高、速效性好和持效期长的特点,有一定的应用开发价值。

Synthesis and Acaricidal Activities of 3-(2,4-Dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl Butane-1-sulfonate,an Analogue of Spirodiclofen

In order to find more highly active acaricides,a new acaricidal compound 3-(2,4-dichlorophenyl)-2-oxo-l-oxaspiro[4.5]dec-3-en-4-yl butane-l-sulfonate (AC-101) was synthesized through a structural modification of spirodielofen.Its formulations 24％ SC and 24％ OD were developed as well.The laboratory bioassay showed that the control effect of AC-101 was 95％ against eggs of Tetranychus cinnabarinus at the concentrate of 1 mg/L.The field trials showed that AC-101 24％ SC and OD provided the control efficacies 95.7％ and 96.2％ respectively against Tetranychus vinnensis on the 14th day after spraying,and the control efficacies were still more than 73.6％ on the 21st day after spraying.As results,AC-101 had a good acaricidal activity with a rapid and persistent effect,and would have potential values for application development.