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乳清蛋白源生物活性肽段序列及其功能
引用本文:李晓东,牛治霞,高莉莉,张柏林. 乳清蛋白源生物活性肽段序列及其功能[J]. 中国乳品工业, 2007, 35(2): 36-42
作者姓名:李晓东  牛治霞  高莉莉  张柏林
作者单位:北京林业大学,生物科学与技术学院食品科学系,北京,100083
基金项目:北京林业大学校科研和教改项目
摘    要:乳清蛋白经酶解产生的肽类除了具有极高的营养价值之外.而且还具有一定的潜在生物活性。目前发现的乳清蛋白源生物活性肽主要有阿片肽、抗高血压肽、抗茵肽和免疫调节肽。综述了上述4种肽的氨基酸序列及其主要功能;对酶解过程中应注意的因素,如酶的类型、水解度、预处理方式、酶的灭活方式、底物纯度和水解过程等理化参数进行了归纳总结。

关 键 词:乳清蛋白  生物活性肽  序列  酶解
文章编号:1001-2230(2007)02-0036-07
修稿时间:2006-08-31

Sequences and functions of bioactive peptides derived from whey protein
LI Xiao-dong,NIU Zhi-xia,GAO Li-li,ZHANG Bo-lin. Sequences and functions of bioactive peptides derived from whey protein[J]. China Dairy Industry, 2007, 35(2): 36-42
Authors:LI Xiao-dong  NIU Zhi-xia  GAO Li-li  ZHANG Bo-lin
Affiliation:School of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China
Abstract:Whey-derived peptides by enzymatic hydrolysis have high nutritional value and many biological functions. The bioactive peptides derived from whey protein consist mainly of opioid, antihypertensive, antibacterial and immunological peptides. This paper presents the amino acid sequence and properties of these bioactive peptides isolated recently from whey proteins. It particularly covered the key parameters used to enzymatically hydrolyze whey proteins in practice. Theses factors affecting the release of bioactive peptides might include specific-enzymes used for the proteolysis of whey protein, the degree of hydrolysis, the pretreatment of protein substrate, the technique used for enzyme inactivation, the purity of the protein substrates, and the physicochemical conditions.
Keywords:whey protein   bioactive peptides   amino acid sequence   enzymatic hydrolysis
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