3,4-二甲基-2,5-二甲酸乙酯噻吩[2,3-b]并噻吩选择性酰肼化 |
| |
引用本文: | 裴学群,吴永祥,颜娇娇,覃文杰,张晓兵,刘洋,曹靖.3,4-二甲基-2,5-二甲酸乙酯噻吩[2,3-b]并噻吩选择性酰肼化[J].化学试剂,2011(7):619-620,642. |
| |
作者姓名: | 裴学群 吴永祥 颜娇娇 覃文杰 张晓兵 刘洋 曹靖 |
| |
作者单位: | 湘潭大学化学学院;教育部环境友好重点实验室; |
| |
基金项目: | 湖南省第二届大学生研究性学习与创新性实验计划资助项目(2009); 湖南省科技厅资助项目(2009FJ-3166) |
| |
摘 要: | 以乙酰丙酮和二硫化碳为原料合成出3,4-二甲基-2,5-二甲酸乙酯噻吩,它在不同溶剂中与过量水合肼反应,得到不同的产物:在乙醇中回流24 h,以66%的产率得到单酰肼化产物3,4-二甲基-噻吩2,3-b]并噻吩-2-甲酸乙酯-5-甲酰肼;以DMF为溶剂80℃反应得到的主要产物是3,4-二甲基-2,5-噻吩2,3-b...
|
关 键 词: | 3 4-二甲基-2 5-二.甲酸乙酯噻吩 单酰肼 双酰肼 |
Selective hydrazidation of diethyl 3,4-dimethylthieno [2,3-b] thiophene-2,5-dicarboxylate |
| |
Abstract: | 3,4-Dimethylthieno2,3-b]thiophene-2,5-dicarboxylate was prepared from acetylacetone and carbon disulfide,then it reacted with excess of hydrazine in different solvent to form various products:refluxing in ethanol for 24 h gave monoacylhydrazine product ethyl 5-(hydrazinecarbonyl) 3,4-dimethylthieno2,3-b]thiophene-2-carboxylate in 66% yield;howbeit diacylhydrazine product 3,4-dimethylthieno 2,3-b]thiophene-2,5-dicarbohydrazide was obtained with DMF as solvent in the reaction and gave 68% yield. |
| |
Keywords: | 3 4-dimethylthieno[2 3-b]thiophene-2 5-dicarboxylate monoacylhydrazine diacylhydrazine |
本文献已被 CNKI 等数据库收录! |
|