Primary cerebral lymphoma following+ kidney transplant: a case report and review of the literature |
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Authors: | F González C Gómez ME Cabrera A Ayala E Roessler |
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Affiliation: | Departamento de Medicina, Facultad de Medicina (Campus Oriente) Universidad de Chile, Hospital del Salvador, Santiago. |
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Abstract: | We report a 30 year old male, presenting eight years after receiving a kidney transplant with intracranial hypertension and two hyperdense masses detected in a brain CAT scan, whose histopathological study revealed a giant cell immunoblastic lymphoma. The patient was successfully treated with chemo and radiotherapy and after 18 months of follow up there is no evidence of tumoral relapse. Immunocompromised patients, specially transplant recipients, had a several fold higher incidence of malignant tumors, specially primary lymphomas of the central nervous system. These are generally of B type, are associated to Epstein Barr virus and have a high mortality. Cancer must be considered in the differential diagnosis of masses of uncertain origin in transplant recipients. |
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