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Photoacoustic Spectroscopy Analysis of Traditional Chinese Medicine
Authors:Lu Chen  Bin-xing Zhao  Hong-tao Xiao  Rong-sheng Tong  Chun-ming Gao
Affiliation:1. Department of Pharmacy, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, No. 32, West Second Section, First Ring Road, Chengdu, People’s Republic of China
2. School of Optoelectronic Information, University of Electronic Science and Technology of China, No. 4, Section 2, North Jianshe Road, Chengdu, People’s Republic of China
Abstract:Chinese medicine is a historic cultural legacy of China. It has made a significant contribution to medicine and healthcare for generations. The development of Chinese herbal medicine analysis is emphasized by the Chinese pharmaceutical industry. This study has carried out the experimental analysis of ten kinds of Chinese herbal powder including Fritillaria powder, etc., based on the photoacoustic spectroscopy (PAS) method. First, a photoacoustic spectroscopy system was designed and constructed, especially a highly sensitive solid photoacoustic cell was established. Second, the experimental setup was verified through the characteristic emission spectrum of the light source, obtained by using carbon as a sample in the photoacoustic cell. Finally, as the photoacoustic spectroscopy analysis of Fritillaria, etc., was completed, the specificity of the Chinese herb medicine analysis was verified. This study shows that the PAS can provide a valid, highly sensitive analytical method for the specificity of Chinese herb medicine without preparing and damaging samples.
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