| 肌苷发酵和分离耦合过程的动力学 |
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| 引用本文： | 李永泉 姚恕. 肌苷发酵和分离耦合过程的动力学[J]. 化学反应工程与工艺, 1992, 8(4): 365-371 |
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| 作者姓名： | 李永泉 姚恕 |
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| 作者单位： | 浙江大学化工系 杭州310027 |
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| 摘 要： | 许多发酵过程都受到高浓度产物的抑制,肌苷发酵亦存在明显的产物反馈抑制作用。为了降低产物抑制效应,采取发酵和离子交换分离产物、流加补料结合起来的耦合发酵方法。本文结合肌苷合成代谢途径,建立了肌苷耦合发酵动力学模型,用于指导工业生产。
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| 关 键 词： | 肌苷 发酵 分离 耦合反应 |
KINETICS ON THE COUPLING PROCESS OF INOSINE FERMENTATION AND SEPARATION |
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| Li Yongquan Yiao Shu Yu Feng Zhen Lianyin. KINETICS ON THE COUPLING PROCESS OF INOSINE FERMENTATION AND SEPARATION[J]. Chemical Reaction Engineering and Technology, 1992, 8(4): 365-371 |
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| Authors: | Li Yongquan Yiao Shu Yu Feng Zhen Lianyin |
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| Affiliation: | Department of Chemical Engineering.Zhejiang Univetsity.Hangzhou 310027 |
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| Abstract: | The inosine fermentation is inhibited by high product concentration.To reduce this product in- hibitation,the strategy of inosing fermentation process was to combine fermentation with ion-ex- change separation m a continuous cyclic system,which contained a 6 L agitated fermentor,a feed chute and a separation column.The kinetic models of inosine fermentation process coupling with separation has been suggested.The model paraineters were simulated by means of Multi-parameter least squares method of regression.The model predictions were in good agreement with experimental data. |
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| Keywords: | Inosine fermentation Separation Coupling process Fermentation kinetics |
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