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Polysaccharides in Lentinus edodes: Isolation,Structure, Immunomodulating Activity and Future Prospective
Authors:Xiaofei Xu  Huidan Yan  Jian Tang  Jian Chen  Xuewu Zhang
Affiliation:1. College of Light Industry and Food Sciences, South China University of Technology , 381 Wushan Road, Guangzhou , 510640 , China;2. Infinitus (China) Company Ltd. , Guangzhou , China;3. College of Light Industry and Food Sciences, South China University of Technology , 381 Wushan Road, Guangzhou , 510640 , China;4. Infinitus (China) Company Ltd. , Guangzhou , China
Abstract:Lentinus edodes has been valued as edible and medical resources. Polysaccharides have been known to be the most potent antitumor and immunomodulating substance in Lentinus edodes. In this review, we summarize the current knowledge of the polysaccharides isolated from Lentinus edodes, including extraction and purification methods, chemical structure and chain conformation, the effects on innate and adaptive immunity and their mechanism, relationship between structure and function, and the future prospects.
Keywords:Lentinus edodes  polysaccharide  lentinan  immunomodulation  antitumor
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