| Abstract: | In 4 experiments, 113 water-deprived male Long-Evans rats were trained to drink in a passive avoidance apparatus. After reaching a latency criterion, Ss were given a single 3-sec, 3-mA footshock. Immediately or 12 hrs after footshock, Ss were given intracranial injections of vehicular saline, norepinephrine (NE), propranolol, or dopamine (DA) into the amygdala, internal capsule, lateral ventricles, or caudate-putamen. Ss were tested for passive avoidance at 30 min or 24 hrs following footshock. No memory deficits were seen as a consequence of short-term retention or because of proactive or toxicity effects. Retention deficits were seen in the 24-hr test only in Ss injected with NE in the amygdala, internal capsule, or lateral ventricles. However, qualitative differences in stress-indicative behaviors were noted in the NE groups and in the DA-amygdala Ss. Results suggest that the noradrenergic system of the amygdala is involved in the long-term processing of the emotional attributes of aversive information. (66 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) |
