| 皮卡佐剂和皮卡狂犬病疫苗的安全性 |
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| 引用本文： | 林海祥,俞永新.皮卡佐剂和皮卡狂犬病疫苗的安全性[J].粉末涂料与涂装,2010,23(1). |
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| 作者姓名： | 林海祥 俞永新 |
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| 作者单位： | 林海祥,LIN Hai-xiang(北京依生兴业科技有限公司,北京,102600);俞永新,YU Yong-xin(中国药品生物制品检定所疫苗一室,北京,100050) |
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| 摘 要： | 皮卡(PICKCa)即聚肌胞注射液,是一种安全、有效的干扰素诱生剂。以皮卡为佐剂制成的皮卡狂犬病疫苗,其安全性不仅符合《中国药典》要求,而且其毒性、抗原含量和防腐剂含量均低于现行人用狂犬病疫苗。本文就皮卡佐剂及皮卡狂犬病疫苗的安全性作一综述。
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| 关 键 词： | 皮卡 佐剂 狂犬病疫苗 安全性 |
Safeties of PICKCa as An Adjuvant and Rabies Vaccine Using The Adjuvant |
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| LIN Hai-xiang,YU Yong-xin.Safeties of PICKCa as An Adjuvant and Rabies Vaccine Using The Adjuvant[J].Chinese Journal of Biologicals,2010,23(1). |
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| Authors: | LIN Hai-xiang YU Yong-xin |
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| Abstract: | As a conjugate of poly I,poly C,kanamycin(K)and calcium chloride(Ca),PICKCa is a safe and effective interferon inducer.The safety of rabies vaccine prepared using PICKCa as an adjuvant met the requirements in Chinese Pharmacopoeia,and its toxicity as well as antigen and preservative contents were lower than those of the current rabies vaccine for human use.The safeties of PICKCa as an adjuvant and rabies vaccine using the said adjuvant are reviewed in this paper. |
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| Keywords: | PICKCa Adjuvant Rabies vaccine Safety |
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