聚吡咯/丝素导电纳米纤维膜的制备及其性能

为开发具有一定导电性的组织再生材料,采用静电纺丝法制备了丝素纳米纤维膜,通过原位氧化聚合获得了聚吡咯/丝素导电性纳米纤维膜,探究了纺丝参数对纳米纤维膜表面形貌的影响,利用四探针测试仪测试了纳米纤维膜的导电性,借助红外光谱仪对纳米纤维膜化学结构进行了表征。结果表明:在质量浓度为0.16 g/mL,推注速度为0.2 mL/h,电压为20 kV,滚筒转速为1 000 r/min的条件下,制备的丝素纳米纤维膜表面规整,珠状物少,纤维平均直径为(520.70±140.81) nm;在吡咯单体浓度为0.3 mol/L,掺杂剂浓度为0.3 mol/L,吡咯单体与FeCl₃的量比为1∶2,聚合时间为6 h条件下,制备的聚吡咯/丝素导电性纳米纤维膜保留了丝素纳米纤维膜原有的纳米纤维结构,电导率达到(0.44±0.07) S/cm。

Preparation and properties of polypyrole/silk fibroin conductive nanofiber membranes

In order to develop tissue regeneration materials with certain electrical conductivity, we prepared silk fibroin nanofiber membranes using electrospinning and further polypyrrole/silk fibroin conductive nanofiber membranes by in-situ oxidative polymerization. The effect of spinning parameters on the surface morphology of nanofiber membrane was studied. The electrical conductivity of nanofiber membrane was tested by the four-point probe. FT-IR spectrometer was used to characterize the chemical structure of nanofiber membrane. The results showed that silk fibroin nanofiber membranes have an even surface with less beads, with an average fiber diameter of (520.70±140.81) nm, when solution concentration was 0.16 g/mL, flow rate 0.2 mL/h, voltage 20 kV, rotating speed 1 000 r/min. Polypyrrole/silk fibroin conductive nanofiber membranes was prepared by in-situ oxidative polymerization, and it retains its original nano fiber structure, and the electrical conductivity is (0.44±0.07) S/cm, when the pyrrole concentration was 0.3 mol/L, dopant concentration 0.3 mol/L, the ratio of fixed pyrrole to oxidant 1∶2, and the polymerization time 6 h.