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Sol-gel derived silica-gel as a controlled delivery system of Andrographis paniculata extract and its anti-microbial efficacy |
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| Authors: | S. Chakraborty S. Biswas J. Sarkar Manna S. Das R. Dey |
| Affiliation: | 1. School of Materials Science and Nanotechnology Jadavpur University, Calcutta, India 2. Department of Metallurgical and Material Engineering Jadavpur University, Calcutta, India 3. Department of Microbiology, Peerless Hospital & B. K. Ray Research centre, Kolkata, India |
| Abstract: | Encapsulation of herbal values into bio-compatible porous silica gel has been attempted with the aim of developing a sustainable, efficient, eco-friendly and controlled drug delivery system using greener traditional alternatives. Aqueous extraction of Andrographis paniculata and entrapment of the same into silica gel has been studied. FTIR peaks prove the presence of herbal values into the silica matrix. 27% of the herbal extract is released in the Phosphate Buffer Saline (PBS) buffer in a period of 240 hours. |
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