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Detection of protein aggregation with a Bloch surface wave based sensor |
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| Authors: | V. PaederAuthor Vitae V. MusiAuthor VitaeL. HvozdaraAuthor Vitae S. HerminjardAuthor VitaeH.P. HerzigAuthor Vitae |
| Affiliation: | Optics & Photonics Technology Laboratory, Institute of Microengineering (IMT), Ecole Polytechnique Fédérale de Lausanne (EPFL), A.-L. Breguet 2, 2000 Neuchâtel, Switzerland |
| Abstract: | We present the innovative application of a Bloch surface wave based sensor to the detection of protein aggregation. In Hen Egg White Lysozyme (HEWL) solutions, aggregates are discriminated from the monomeric forms in a label-free detection scheme. |
| Keywords: | Bloch Surface Waves (BSW) Optical sensor Protein detection Protein aggregation |
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