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Back Cover: Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback‐Modulation Handles (ChemMedChem 12/2015) |
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| Authors: | Dr Ingo V Hartung Dr Roland Neuhaus Dr Arne Scholz Dr Gerhard Siemeister Dr Jens Geisler Dr Roman C Hillig Dr Oliver von Ahsen Dr Marion Hitchcock |
| Affiliation: | 1. Medicinal Chemistry Berlin, Bayer HealthCare AG, Berlin, Germany;2. Research Pharmacokinetics, Bayer HealthCare AG, Berlin, Germany;3. Global Therapeutic Research Group Oncology, Bayer HealthCare AG, Berlin, Germany;4. Structural Biology, Bayer HealthCare AG, Berlin, Germany;5. Global Biomarker Research, Bayer HealthCare AG, Berlin, Germany;6. Medicinal Chemistry Berlin, Bayer HealthCare AG, Berlin, GermanyFormer affiliation and address during this project. |
| Abstract: | |
| Keywords: | feedback activation inhibitors kinases MEK oncology structure-based drug design |