黄芩及其水煎废渣中黄芩苷的提取和抗氧化活性比较

研究了黄芩及其水煎废渣中黄芩苷的提取工艺，并比较了两种提取物中黄芩苷的含量和抗氧化活性．通过正交试验得到的黄芩中黄芩苷的水煎煮法提取工艺为：提取3次，料液比1：15，每次提取1．5h；水煎煮黄芩废渣中黄芩苷的醇法超声强化提取工艺为：乙醇体积分数70％，料液比1：15，超声功率150W，提取时间30min；从黄芩及其水煎废渣中提取黄芩苷粗品的得率分别为4．57％和7．789／6，但两者黄芩苷含量和抗氧化活性相近．

COMPARISON OF THE EXTRACTION AND ANTI-OXIDATION ACTIVITY OF BAICALIN FROM BAIKAL SKULLCAP ROOT AND ITS DECOCTED RESIDUE

A lot of bio-active ingredients remains in the wastes of Chinese herbal medicines decocted by water, which can be reused as a resource. This paper investigated the optimum conditions of extracting baicalin by decocting baikal skullcap root （BSR） firstly and then pre- cipitating baicalin with acid, the optimum technical conditions of extracting baicalin in decocted BSR wastes by combining use of alcohol and ultrasound, the baicalin content in 2 extracts by HPLC, and the anti-oxidation activity of the 2 extracts. As a result, the optimum conditions of extracting baicalin by decocting BSR are as follows： the ratio of feed to liquid 1 ： 10, extracting time 1.5 h, and extracting times 3. The optimum technical conditions of extracting baicalin from decocted BSR residue are. the ethanol volume fraction 70%, the ratio of feed to liquid 1 ： 15, power 150 W, and extraction time 30 min. The yield of raw baicalin from BSR and its decocted residue are 4. 57% （w/w） and 7. 78% （w/w） respectively, and the 2 extracts have close baicalin content and anti-oxidation activity.