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Gut microbiota modulation and immune boosting properties of prebiotic dragon fruit oligosaccharides |
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| Authors: | Nattha Pansai Korawan Chakree Chutha Takahashi Yupanqui Pritsana Raungrut Niracha Yanyiam Santad Wichienchot |
| Affiliation: | 1. Faculty of Agro-Industry, Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand;2. Interdisciplinary Graduate School of Nutraceutical and Functional Food (IGS-NFF), Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand;3. Department of Biomedical Sciences, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110 Thailand;4. Department of Pharmacology, Faculty of Science, Prince of Songkla University, Songkhla, 90110 Thailand |
| Abstract: | This is the first report of the evaluation of suitability for consumption of dragon fruit oligosaccharide (DFO) and its efficacy on gut microbiota modulation and in boosting the gut immune response in rats. The DFO produced significantly increased faecal bifidobacteria and lactobacilli but decreased bacteroides and clostridia. The DFO also showed immune-response boosting properties by significantly increasing the plasma immunoglobulin A and G concentrations. In addition, it was confirmed by blood chemistry analysis and histology of the colon of the rats that DFO is suitable for the consumption. These results suggest that DFO is a potentially novel source of prebiotic ingredients with probiotic-stimulation and immune boosting properties. |
| Keywords: | Dragon fruit oligosaccharides gut microbiota immune boosting prebiotic |