葡萄糖脱水制备5-羟甲基糠醛的研究

研究了Br（o）nsted-Lewis复合催化体系催化葡萄糖脱水制备5-羟甲基糠醛,详细考察了溶剂种类和用量、催化体系种类和用量、反应时间和反应温度等因素对5-羟甲基糠醛收率的影响,得到最佳工艺条件：葡萄糖2.0g,复合催化体系HCl-CrCl3m（HCl）∶m（CrCl3·6H2O）=5∶1]0.6 g,正丁醇20 mL,反应时间15 min,反应温度200℃.在该反应条件下,5-羟甲基糠醛的收率达42.5％.结果表明,同单酸型的催化剂相比,复合催化体系更有利于葡萄糖脱水制备5-羟甲基糠醛.

Preparation of 5-hydroxymethylfurfural by dehydration of glucose

The preparation of 5-hydroxymethylfurfural from glucose was studied in the presence of Br（o）nsted-Lewis composite catalytic system.The effects of reaction conditions,such as solvents,catalysts,reaction time and reaction temperature,on the yield of 5-hydroxymethylfurfural were examined.The optimum reaction conditions were obtained as follow：glucose 2.0 g,composite catalytic system HC1-CrCl3 （mass ratio 5 ∶ 1） 0.6 g,n-butyl alcohol 20 mL,reaction time 15 min and reaction temperature 200 ℃.Under above optimum conditions,the conversion of glucose was 90.4 ％,and the yield of 5-hydroxymethylfurfural reached 42.5 ％.The results indicated that,composite catalytic system is more conducible to preparation of 5-hydroxymethylfurfural by dehydration of glucose compared with the single-acid catalyst.