Synthesis,characterization and in-vitro biocompatibility of electrophoretic deposited europium-doped calcium silicate on titanium substrate |
| |
| Affiliation: | 1. Department of Mechanical Engineering, Faculty of Engineering, Universiti Malaya, 50603 Kuala Lumpur, Malaysia;2. Department of Biomedical Engineering, Faculty of Engineering, Universiti Malaya, 50603 Kuala Lumpur, Malaysia;3. School of Mechanical and Aerospace Engineering Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore;4. Department of Chemical Engineering, Faculty of Engineering, Universiti Malaya, 50603 Kuala Lumpur, Malaysia;5. Centre of Advanced Materials, Faculty of Engineering, Universiti Malaya, 50603 Kuala Lumpur, Malaysia;1. School of Materials Science and Engineering, Shanghai Institute of Technology, Shanghai 201418, China;2. Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang 621900, China;3. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China;1. Department of Materials Science and Engineering, School of Materials and Chemical Technology, Tokyo Institute of Technology, Tokyo 152-8550, Japan;2. Laboratory for Zero-Carbon Energy, Institute of Innovative Research, Tokyo Institute of Technology, Tokyo 152-8550, Japan;1. School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China;2. Tangshan Research Institute, Beijing Institute of Technology, Tangshan 063007, China;3. School of Physics and Electronic Information, Yan''an University, Yanan 716000, China;1. MOE Key Laboratory of New Processing Technology of Nonferrous Metals and Materials, Guangxi Key Laboratory of Optical and Electronic Materials and Devices, College of Materials Science and Engineering, Guilin University of Technology, Guilin 541004, PR China;2. Spallation Neutron Source Science Centre, Dongguan 523803, PR China;3. Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, PR China;4. Songshan Lake Materials Laboratory, Dongguan, Guangdong 523808, PR China;5. College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, PR China;1. State Key Laboratory of Environmentally-friendly Energy Materials, School of Materials Science and Chemistry, Southwest University of Science and Technology, Mianyang 621010, PR China;2. State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu, Sichuan, PR China;3. Southwest Institute of Applied Magnetics, Mianyang 621000, PR China |
| |
| Abstract: | Europium (Eu) has attracted attention to be incorporated as biologically active ions to achieve different biological and functional properties of biomaterials. In this study, calcium silicate (CS) coatings doped with different amount of Eu (up to 10 mol%) were successfully formed on titanium substrates via electrophoretic deposition. A low amount of Eu (2.5 mol%) gave a relatively denser coating and improved coating adhesion strength (～3.3 N). All Eu–CS coatings provided good apatite forming ability, yet lower degradation rate, as compared to CS coating. Moreover, it was observed that the human fetal osteoblast (hFOB) cells could attach and proliferate on all Eu–CS coatings, suggesting their biocompatible nature. Eu2.5CS not only showed comparable cell proliferation with CS, but also enhanced the osteogenic activity of the CS coating. All results suggested that Eu2.5CS coatings are promising coating materials for biomedical implants, particularly bone tissue engineering applications. |
| |
| Keywords: | Calcium silicate Europium Coating Electrophoretic deposition Biocompatibility |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
