Treatment of persistent glaucoma secondary to periocular corticosteroids |
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Authors: | L Akduman AE Kolker DL Black LV Del Priore HJ Kaplan |
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Affiliation: | Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110-1096, USA. |
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Abstract: | PURPOSE: To describe two patients with uveitis who developed increased intraocular pressure that was unresponsive to maximum medical therapy eight and 13 months after periocular injection of triamcinolone acetonide. METHODS: Excised periocular tissue was analyzed for corticosteroid activity by gas chromatography and mass spectrometry. RESULTS: Excision of the periocular tissue, which contained visible triamcinolone acetonide, resulted in a normal intraocular pressure within 14 days in both patients. Analysis of the excised tissue disclosed residual corticosteroid in one of the two patients. CONCLUSION: Removal of periocular tissue containing injected corticosteroids may facilitate the management of patients developing increased intraocular pressure unresponsive to maximum medical therapy. |
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