Three dimensional electron spin resonance (ESR) imaging of internal organs in living mice |
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Authors: | T Masumizu K Fujii M Kohno S Nagai Y Odagaki M Imanari A Mori L Packer |
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Affiliation: | ESR Application Laboratory, Application & Research Center, Analytical Instruments Division, JEOL LTD., Tokyo, Japan. |
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Abstract: | In vivo electron spin resonance imaging (ESR imaging) was applied to living mice after peroral administration of a nitroxide radical spin probe. A 3D ESR imaging procedure was applied in vivo in order to obtain the exact distribution of the spin probe in a living animal. The imaging pictures demonstrated that the administered spin probe was firstly located in the stomach, then delivered to the liver, kidney and heart of the animal. |
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