点核积分计算6711型~(125)I籽粒源剂量参数

使用点核积分方法计算6711型~(125)I籽粒源参数,根据美国医学物理学家协会(American Association of Physicists in Medicine,AAPM)TG-43U1号报告推荐的剂量参数计算公式,可以获得6711型~(125)I籽粒源各参数。与AAPM TG-43U1推荐值比较,剂量常数相差6.76%,径向剂量函数值(不包括0.1 cm、0.15 cm、0.25 cm)最大相差2.27%,最小相差0.02%;与MCNP5(A General N-Particle Transport Code,Version 5)方法计算结果比较,剂量常数相差6.19%,径向剂量函数值(不包括0.1 cm、0.15 cm、0.25 cm)最大相差6.65%,最小相差0.06%。结果与推荐值符合较好,证明点核积分能够应用于籽粒源剂量参数计算。

Determination of dosimetric characteristics for the model number 6711125 I seed source with the point-kernel method

Background: The125 I brachytherapy source has become a popular treatment option in the treatment various tumors, in order to reduce the risk of surrounding normal tissue, it is important to know the dosimetric characteristics of seed source.Purpose: The aim is to develop a reliable and saving time method for calculating the dosimetric parameters of seed source.Methods: Dosimetric parameters (dose rate constant, radial dose function and anisotropy function) of the model number 6711125 I seed source are calculated with point-kernel method following American association of physicists in medicine (AAPM) TG-43U1 recommendations.Results: The result was compared with the relative data recommended by AAPM TG-43U1 and Monte-Carlo (M-C) method. Dose rate constant with AAPM was in agreement with 6.76%, and that with M-C is 6.19%; radial dose function (except 0.1 cm, 0.15 cm and 0.25 cm) with AAPM is within 0.02%?2.27%, and that with M-C is within 0.06%?6.65%.Conclusion: The point-kernel method can be applicable to calculate the dosimetric characteristics of seed sources.