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Glabridin,an isoflavan from licorice root,upregulates paraoxonase 2 expression under hyperglycemia and protects it from oxidation
Authors:Itamar Yehuda  Zecharia Madar  Alicia Leikin‐Frenkel  Andrea Szuchman‐Sapir  Faiga Magzal  Gilad Markman  Snait Tamir
Affiliation:1. Laboratory of Human Health and Nutrition Sciences, MIGAL‐Galilee Research Institute, Kiryat‐Shmona, Israel;2. The Hebrew University of Jerusalem, The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, Rehovot, Israel;3. Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel;4. Sheba Medical Center, Bert W. Strassburger Lipid Center, Tel‐Hashomer, Israel;5. Tel‐Hai College, Faculty of Sciences and Technology, Upper Galilee, Israel;6. Eliachar Research Laboratory, Galilee Medical Center, Nahariya, Israel;7. Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel
Abstract:
Keywords:Diabetes  Glabridin  Mass spectroscopy  Oxidative stress  Paraoxonase 2  Tryptophan‐fluorescence quenching
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