导电分子印迹膜化学修饰电极的制备及其对胭脂红的电化学检测

报道了一种聚丙烯酰胺(PAAM)-植酸(PA)-聚多巴胺(PDA)导电分子印迹膜(PAAM-PA-PDA MIP)化学修饰电极的制备、表征及其在电化学定量检测食品添加剂胭脂红(P4R)中的应用。即通过原位电聚合和碱液洗脱的方法在玻碳电极(GCE)表面制得具有分子识别作用的导电分子印迹膜(PAAM-PA-PDA MIP)化学修饰电极，并利用SEM、循环伏安法(CV)及交流阻抗法(EIS)对该导电分子印迹膜化学修饰电极的表面形貌和电化学性能进行表征。研究结果表明该方法所制备的导电分子印迹膜化学修饰电极具有良好的电化学检测性能和应用前景，其对P4R的线性检测区间为10~200 μmol/L，灵敏度为0.085 A/mol/L，检测限可达23.6 nmol/L，并可有效地应用于P4R实际样品的分析检测。 

Preparation of conductive molecularly imprinted membrane chemically modified electrode and electrochemical detection of Ponceau 4R

A polyacrylamide-phytic acid-polydopamine conductive molecularly imprinted membrane (PAAM-PA-PDA MIP) chemically modified electrode was prepared, characterized and applied to the quantitative detection of food additive Ponceau 4R (P4R). Based on the in-situ electrochemical polymerization and alkaline elution, a PAAM-PA-PDA MIP chemically modified electrode with molecular recognition was prepared by the modification of surface of a glassy carbon electrode (GCE) with PAAM-PA-PDA MIP. In addition, as-prepared PAAM-PA-PDA MIP chemically modified electrode was characterized by SEM, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). It is found that the PAAM-PA-PDA MIP chemically modified electrode could be applied in the electrochemical detection of P4R with linear detection range from 10 μmol/L to 200 μmol/L, high sensitivity of 0.085 A/mol/L and low detection limit of 23.6 nmol/L, which presents potential application in the practical detection of P4R.