| 三种蓝莓抗氧化及抗Hep G2细胞增殖活性的比较分析 |
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| 引用本文： | 梁泽明,陈春,伍惠仪,胡心怡,王睿飞,余以刚. 三种蓝莓抗氧化及抗Hep G2细胞增殖活性的比较分析[J]. 现代食品科技, 2019, 35(6): 48-55 |
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| 作者姓名： | 梁泽明 陈春 伍惠仪 胡心怡 王睿飞 余以刚 |
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| 作者单位： | 华南理工大学食品科学与工程学院,广东广州,510640;劲家庄(惠州)健康食品有限公司,广东惠州,516000 |
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| 基金项目： | 国家重点研发计划项目（2018YFC1602201）；广东省重点领域研发计划项目（2019B020212003） |
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| 摘 要： | 以三种常见市售蓝莓[大兴安岭野生蓝莓(Vaccinium uliginosum L.)、贵州兔眼蓝莓(Vaccinium ashei Reade)和智利蓝莓(Vaccinium corymbosum L.)]为研究对象,研究了其总多酚、总黄酮和总花色苷含量及抗氧化活性和抗Hep G2细胞增殖活性,并分析了活性成分含量与活性功能的相关性。结果表明:大兴安岭野生蓝莓的总多酚、总黄酮和总花色苷的含量及DPPH和ABTS自由基的清除能力显著高于贵州蓝莓和智利蓝莓(p0.05);细胞抗氧化实验结果表明大兴安岭野生蓝莓的CAA(CellularAntioxidant Activity)值显著高于贵州蓝莓和智利蓝莓,为202.40±6.33μmolQE/100g鲜果(非PBS清洗处理时)和65.40±3.04μmolQE/100g鲜果(PBS清洗处理时)(p0.05);三种蓝莓均对HepG2细胞增殖有较强的抑制作用,其中大兴安岭野生蓝莓的抗HepG2细胞增殖的半数有效浓度EC50显著低于贵州蓝莓和智利蓝莓,分别为150.41±7.82、212.87±13.10和221.53±12.53 mg/mL(p0.05);蓝莓的CAA值与总多酚和总黄酮含量之间显著相关,抗Hep G2细胞增殖的EC50值与总多酚、总黄酮和总花色苷含量之间显著相关(p0.05)。以上结果表明大兴安岭野生蓝莓具有极大的开发利用优势。
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| 关 键 词： | 蓝莓 花色苷 细胞抗氧化活性 抗增殖活性 |
| 收稿时间： | 2018-11-05 |
Comparative Analysis of Antioxidant Activity and Anti-proliferative Activity against Hep G2 Cells of Three Blueberry Varieties |
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| LIANG Ze-ming,CHEN Chun,WU Hui-yi,HU Xin-yi,WANG Rui-fei and YU Yi-gang. Comparative Analysis of Antioxidant Activity and Anti-proliferative Activity against Hep G2 Cells of Three Blueberry Varieties[J]. Modern Food Science & Technology, 2019, 35(6): 48-55 |
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| Authors: | LIANG Ze-ming CHEN Chun WU Hui-yi HU Xin-yi WANG Rui-fei YU Yi-gang |
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| Affiliation: | (1.School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China),(2.Jin Jia Zhuang (Hui Zhou) Health Food Co. Ltd., Huizhou, 516000, China),(1.School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China),(1.School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China),(1.School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China) and (1.School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China) |
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| Abstract: | |
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| Keywords: | blueberry anthocyanin cellular antioxidant activity anti-proliferative activity |
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