|
|||||
|
|
Imaging the sialome during zebrafish development with copper-free click chemistry |
|
| Authors: | Dehnert Karen W Baskin Jeremy M Laughlin Scott T Beahm Brendan J Naidu Natasha N Amacher Sharon L Bertozzi Carolyn R |
| Affiliation: | Department of Chemistry, University of California, B84 Hildebrand Hall 1460, Berkeley, CA 94720, USA. |
| Abstract: | The sialome comprises sialylated glycoproteins and glycolipids that play essential roles in cell-cell communication. Using azide-modified molecular precursors of sialic acids and copper-free click chemistry, we visualized the spatiotemporal dynamics of the sialome in live zebrafish embryos. |
| Keywords: | bioorthogonal chemistry embryonic development fluorescence imaging glycosylation sialic acids |
| 本文献已被 PubMed 等数据库收录！ | |