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ON HIGH-POROUS CERAMIC FOR PHARMACEUTICAL CARRIER
引用本文:孙淑珍,邬江新,周向勤,陈安民,王泰仪,李振凡. ON HIGH-POROUS CERAMIC FOR PHARMACEUTICAL CARRIER[J]. 武汉理工大学学报(材料科学英文版), 1996, 0(4)
作者姓名:孙淑珍  邬江新  周向勤  陈安民  王泰仪  李振凡
作者单位:Inst.of Mater.Sci.and Tech..Wuhan Univ.of Tech..Wuhan 430070.China,Inst.of Mater.Sci.and Tech..Wuhan Univ.of Tech..Wuhan 430070.China,Inst.of Mater.Sci.and Tech..Wuhan Univ.of Tech..Wuhan 430070.China,Tongji Hospital,Tonji Medical University,Wuhan 430013.P.R.China,Tongji Hospital,Tonji Medical University,Wuhan 430013.P.R.China,Tongji Hospital,Tonji Medical University,Wuhan 430013.P.R.China
基金项目:Funded by China Public Health Department
摘    要:A kind of hydroxyapatite (HA) high-porous ceramic (HPC) which is used as pharmaceutical carrier for spinal tuberculosis treating is investigated. the structure of HPC is analyzed and physicochemical properties are determined. Experiments and clinical application show that when HPC carrying antituberculosis drug was imbedded in the tuberculosis focus-the drug in effective concentration can continuously be released for 27 weeks-also-the drug concentration achieves high local level but low systematic level -thus the curative effect can distinctly enhanced.


ON HIGH-POROUS CERAMIC FOR PHARMACEUTICAL CARRIER
Sun Shuzhen Wu Jiangxin Zhou XiangqinInst. of Mater. Sci. and Tech. . Wuhan Univ. of Tech. . Wuhan . China Chen Anmin Wang Taiyi Li ZhenfanTongji Hospital,Tonji Medical University,Wuhan .P. R.China. ON HIGH-POROUS CERAMIC FOR PHARMACEUTICAL CARRIER[J]. Journal of Wuhan University of Technology. Materials Science Edition, 1996, 0(4)
Authors:Sun Shuzhen Wu Jiangxin Zhou XiangqinInst. of Mater. Sci.  Tech. . Wuhan Univ. of Tech. . Wuhan . China Chen Anmin Wang Taiyi Li ZhenfanTongji Hospital  Tonji Medical University  Wuhan .P. R.China
Affiliation:Sun Shuzhen Wu Jiangxin Zhou XiangqinInst. of Mater. Sci. and Tech. . Wuhan Univ. of Tech. . Wuhan 430070. China Chen Anmin Wang Taiyi Li ZhenfanTongji Hospital,Tonji Medical University,Wuhan 430013.P. R.China
Abstract:A kind of hydroxyapatite (HA) high-porous ceramic (HPC) which is used as pharmaceutical carrier for spinal tuberculosis treating is investigated. the structure of HPC is analyzed and physicochemical properties are determined. Experiments and clinical application show that when HPC carrying antituberculosis drug was imbedded in the tuberculosis focus.the drug in effective concentration can continuously be released for 27 weeks.also.the drug concentration achieves high local level but low systematic level .thus the curative effect can distinctly enhanced.
Keywords:high-porous ceramic  hydroxyapatite  pharmaceutical carrier  spinal tuberculosis
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