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| 3-甲氧基丙酸甲酯合成工艺研究 | |
| 引用本文： | 秦丙昌,陈静,廖新成,屈凌波.3-甲氧基丙酸甲酯合成工艺研究[J].应用化工,2007,36(6):596-598. |
| 作者姓名： | 秦丙昌 陈静 廖新成 屈凌波 |
| 作者单位： | 1. 郑州大学,化学系,河南,郑州,450052;安阳师范学院,化学化工学院,河南,安阳,455000 2. 安阳师范学院,化学化工学院,河南,安阳,455000 3. 郑州大学,化学系,河南,郑州,450052 |
| 摘 要： | 以甲醇和丙烯酸甲酯(MA)为原料,甲醇钠为催化剂,合成了3-甲氧基丙酸甲酯(MMP)。用正交实验法优化了反应条件,结果表明,当n(甲醇)∶n(丙烯酸甲酯)=1.2∶1,n(甲醇钠)∶n(丙烯酸甲酯)=0.02∶1,反应温度50℃,反应时间3.5 h时,MMP的产率可达97%以上。将分馏时所得前馏分进行套用后,MMP的产率可达98.9%。气相色谱分析表明,产品纯度在99.6%以上。 |
| 关 键 词： | 3-甲氧基丙酸甲酯 丙烯酸甲酯 甲醇 甲醇钠 加成反应 |
| 文章编号： | 1671-3206（2007）06-0596-03 |
| 修稿时间： | 2007-03-12 |
Study on the synthetic process of methyl 3-methoxypropionate |
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| QIN Bing-chang,CHEN Jing,LIAO Xin-cheng,QU Ling-bo.Study on the synthetic process of methyl 3-methoxypropionate[J].Applied chemical industry,2007,36(6):596-598. | |
| Authors: | QIN Bing-chang CHEN Jing LIAO Xin-cheng QU Ling-bo |
| Affiliation: | 1. Department of Chemistry, Zhengzhou University, Zhengzhou 450052, China ;2. College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, China |
| Abstract: | Methyl 3-methoxypropionate(MMP)was prepared from methanol and methyl acrylate(MA) using sodium methoxide as catalyst.The reaction conditions were optimized through orthogonal method.The results shows that the optimum preparation conditions were as follows:the mole ratio of methanol to MA was 1.2 ∶1,mole ratio of sodium methoxide to MA was 0.02 ∶1,reaction temperature was 50 ℃ and reaction time was 3.5 h.Under such conditions,more than 97% yield of MMP could be obtained.Experiments also proved that when the head fraction was cyclically used,the yield of MMP could reach 98.9%.Determined by gas chromatography,the purity of the product(MMP) was more than 99.6%. |
| Keywords: | methyl 3-methoxypropionate methyl acrylate methanol sodium methoxide addition reaction |
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