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Structural basis for the high thermal stability and optimum pH of sphingomyelinase C from Streptomyces griseocarneus |
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| Authors: | Ikuhide Fujisawa Hiroaki Hamana Yu Tomita Yusaku Matsumoto Kazutaka Murayama Daisuke Sugimori |
| Affiliation: | 1. Department of Applied Chemistry and Life Science, Graduate School of Technology, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempakucho, Toyohashi, Aichi 657-8501, Japan;2. Graduate School of Biomedical Engineering, Tohoku University, 2-1 Seiryo, Aoba, Sendai 980-8575, Japan;3. Materials Science Course, Faculty of Symbiotic Systems Science, Fukushima University, 1 Kanayagawa, Fukushima 960-1296, Japan |
| Abstract: | |
| Keywords: | Sphingomyelinase C Central metal-binding site Structural diversity Hydrogen bond network Coordinated water molecules Thermostability |
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