肝癌患者血清瘦素表达及其临床意义

目的探讨肝癌患者血清瘦素（Leptin）的变化及其意义。方法研究分肝癌组（104例）、肝癌术后组（86例）及正常对照组（100例），采用全自动生化分析仪检测各组血清中总胆固醇（TC）、甘油三酯（TG）、碱性磷酸酶（ALP）及总胆红素（STB）等生化指标并用放射免疫法检测Leptin及甲胎蛋白（AFP）。结果与正常对照组相比，肝癌组血清TG、TC、ALP、STB、Leptin、AFP及肝癌术后组TG、Leptin、AFP含量均显著升高（P〈0．05），同时与肝癌组相比，肝癌术后组Leptin、AFP含量明显降低（P〈O．05），TC、TG、ALP、STB含量无明显改变。Leptin与TC、TG呈正相关，而与AFP、ALP、STB无相关性。结论Leptin参与肝癌的发生发展，其作用机制可能与促进肝癌组织新生血管形成有关。

Leptin expression in serum of liver cancer patients and its clinical significance

An innovative coupling fiber-optic ultrasonic sensor for the measurement of ultrasonic signals is presented, and its working principle is discussed at the same time.An ultrasonic signal detection system consists of a coupling fiber-optic ultrasonic sensor,a photoelectric conversion control unit and a software package for processing acquired signals with high resolution has been successfully developed.The ability of the sensor is examined through the detection of a 150 kHz continuous ultrasonic wave,a pulsed...