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| 苦荞胚油对高脂血大鼠血脂及脂质过氧化作用的影响 | |
| 引用本文： | 王敏,魏益民,高锦明. 苦荞胚油对高脂血大鼠血脂及脂质过氧化作用的影响[J]. 中国粮油学报, 2006, 21(4): 45-49 |
| 作者姓名： | 王敏 魏益民 高锦明 |
| 作者单位： | 1. 西北农林科技大学食品科学与工程学院,杨凌,712100 2. 西北农林科技大学食品科学与工程学院,杨凌,712100;中国农业科学院农产品加工研究所,北京,100094 3. 西北农林科技大学生命学院,杨凌,712100 |
| 基金项目： | 科技部攻关项目;陕西省西安市科技攻关项目 |
| 摘 要： | 目的：研究苦荞胚油对实验性高脂血症大鼠的降脂和抗氧化作用.方法：7w龄,60只Wistar大鼠,按体重随机分为6组;除正常对照组外,其余各组用高脂饲料制作高脂血症动物模型,其中苦荞胚油分为0.2、0.5、1.0g/kg剂量组;以绞股兰总苷片为阳性对照组,剂量为0.032g/kg;正常组、模型组为10 mL/kg蒸馏水,各组每天灌胃一次,连续6周.最终测定血脂、肝脂和抗氧化相关指标.结果：与模型组相比,苦荞胚油各剂量组血清TG和肝脏MDA降低均达到极显著（P＜0.01）水平;其中中剂量组降脂和抗氧化效果突出,其血清TC、血清MDA和肝脏TG降低均达到显著水平（P＜0.05）,肝脏TC降低达到非常显著水平（P＜0.01）.结论：苦荞油有显著的降血脂、肝脂、抗肝脂氧化作用,对其降脂功能的利用应予以足够的重视. |
| 关 键 词： | 苦荞 油脂 血脂 肝脂 丙二醛 |
| 收稿时间： | 2005-06-19 |
| 修稿时间： | 2005-06-19 |
Cholesterol Lowering Effect of Tartary Buckwheat Germ Oil in Hypercholesterolemic Rat |
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| Wang Min,Wei Yimin,Gao Jinming. Cholesterol Lowering Effect of Tartary Buckwheat Germ Oil in Hypercholesterolemic Rat[J]. Journal of the Chinese Cereals and Oils Association, 2006, 21(4): 45-49 | |
| Authors: | Wang Min Wei Yimin Gao Jinming |
| Affiliation: | 1. College of Food Science and Engineering, Northwest Agriculture and Forestry University , Yangling 712100 ; Institute of Agro - Food Science and Technology, The Chinese Academy of Agricultural Sciences, Beijing 100094; 3. College of Life Science, Northwest Agriculture and Forestry University, Yangling 712100 |
| Abstract: | Objective: To study cholesterol-lowering effect by tartary buckwheat germ oil in hypercholesterolemic rat.Methods: 60 Wistar rats were divided randomly into 6 groups according to body weight.Except normal control group(NC),every group was hypercholesterolemic model.NC and high-fat control group(HFC) were given distilled water 10mL/kg;positive control group(PC) was given Gynostemma Pantaphyllum total glucoside tablet 0.032 g/kg;tartary buckwheat germ oil was added with dosage of 0.2,0.5,1.0 g/kg respectively by gavage one time a day for 6 weeks.TG,TC,HDL-C,apoA_(1,)apoB and MDA were detected respectively.Results: Compared with HFC,tartary buckwheat germ oil lowers serum TG(P<0.01) and hepatic MDA(P<0.01) in all groups.Medium dosage group has significant hypolipidemic effects: serum TC decreased(P<0.05),hepatic TG lowered(P<0.05),hepatic TC lowered(P<0.01),and plasma MDA lowered(P<0.05).Conclusion: tartary buckwheat germ oil exhibits significant lowering effects for serum lipids and hepatic lipids,and effect of antioxidation. |
| Keywords: | tartary buckwheat oil serum lipids hepatic lipids malondialdehyde |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |