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NAD+对X-射线照射后L02细胞的影响
引用本文:姜润亭.NAD+对X-射线照射后L02细胞的影响[J].辽东学院学报(自然科学版),2011,18(1):53-58.
作者姓名:姜润亭
作者单位:辽东学院医学院,辽宁,丹东,118000
摘    要:通过实验观察氧化型辅酶I(NAD+)对辐射损伤的人正常肝细胞株L02细胞的影响,阐述了氧化型辅酶I(NAD+)抗辐射损伤作用及其机制.结果表明:NAD+能够对抗X射线引起的L02细胞凋亡的增加,恢复细胞增殖活性.进而为研究医源性和非医源性辐射损伤防护、寻求新型放射防护剂提供一种新的思路.

关 键 词:NAD+  X-射线  电离辐射  凋亡  L02细胞株

Oxidized Coenzyme I (NAD +): Effect on X-ray Radiated L02 Cells
JIANG Run-ting.Oxidized Coenzyme I (NAD +): Effect on X-ray Radiated L02 Cells[J].Journal of Liaodong University:Natural Sciences,2011,18(1):53-58.
Authors:JIANG Run-ting
Affiliation:JIANG Run-ting(College of Medicine,Eastern Liaoning University,Dandong 118000,China)
Abstract:Effect of oxidized Coenzyme I(NAD+) on L02 cells of normal human liver cell lines injured by X-ray was experimentally studied.The function and mechanism of oxidized Coenzyme I(NAD+) of resisting to radiation damage were discussed.The results show that NAD+ can restrain the apoptosis of L02 cells induced by X-ray and make them regain proliferation activity.This study can provide a new way for developing protecting agent of iatrogenic and non-iatrogenic radiation injuries.
Keywords:NAD  X-ray  radiation  apoptosis  L02 cell  
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