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弥漫性轴索损伤实验装置的研制和应用
引用本文:赵志球,谢叻,马延斌,王洪财,庄小龙. 弥漫性轴索损伤实验装置的研制和应用[J]. 中国机械工程, 2010, 0(7)
作者姓名:赵志球  谢叻  马延斌  王洪财  庄小龙
作者单位:上海交通大学国家数字化制造技术中心;上海交通大学医学院附属第三人民医院;
基金项目:国家自然科学基金资助项目(60873131); 国家863高技术研究发展计划资助项目(2009AA01Z313)
摘    要:为研究弥漫性轴索损伤(DAI)问题,研制了一套稳定性高、重复性好且能比较真实地模拟DAI临床损伤机制的实验装置。详细阐述了实验装置的设计过程,包括驱动力的选择、联动结构设计、限位固定块的设计和传感器的选择等。最后通过大鼠实验验证了实验装置的可行性和优越性。

关 键 词:弥漫性轴索损伤(DAI)  致伤装置  扭转弹簧  联动结构  

Research and Application on Diffuse Axonal Injury Experimental Device
Zhao Zhiqiu Xie Le Ma Yanbin Wang Hongcai Zhuang Xiaolong.National Digital Manufacturing Technology Center,Shanghai Jiao Tong University,Shanghai,.No. People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. Research and Application on Diffuse Axonal Injury Experimental Device[J]. China Mechanical Engineering, 2010, 0(7)
Authors:Zhao Zhiqiu Xie Le Ma Yanbin Wang Hongcai Zhuang Xiaolong.National Digital Manufacturing Technology Center  Shanghai Jiao Tong University  Shanghai  .No. People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Affiliation:Zhao Zhiqiu1 Xie Le1 Ma Yanbin2 Wang Hongcai2 Zhuang Xiaolong11.National Digital Manufacturing Technology Center,Shanghai Jiao Tong University,Shanghai,2000302.No.3 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,201900
Abstract:Diffuse axonal injury(DAI),which is the most important types of brain injury,is the main cause of death,serious disability and vegetative being.In order to study the DAI,a experimental device with high stability and good reproducibility was designed,which can simulate the clinical process of the DAI injury.This paper described the design process in detail,such as the choosing of the driving force,the design of the linked structure,the design of limited block and the choice of sensors.Finally,the verificatio...
Keywords:diffuse axonal injury(DAI)  injury-causing device  torsional spring  linked structure  
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