| Petri网在代谢网络模块化分析中的应用 |
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| 引用本文： | 丁德武,黄海生,吴璞,王汝传. Petri网在代谢网络模块化分析中的应用[J]. 计算机工程与应用, 2010, 46(33): 218-220. DOI: 10.3778/j.issn.1002-8331.2010.33.062 |
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| 作者姓名： | 丁德武 黄海生 吴璞 王汝传 |
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| 作者单位： | 1. 池州学院,数学与计算机科学系,安徽,池州,247000
2. 南京邮电大学,计算机学院,南京,210003 |
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| 基金项目： | 国家自然科学基金，国家高技术研究发展计划(863)，安徽省教育厅自然科学项目 |
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| 摘 要： | 代谢网络的模块化分析有助于理解网络的结构和功能。然而，当前众多的模块化分析方法大多将代谢网络考虑为普通的复杂网络，所得模块的生物学意义较低。对枯草芽孢杆菌的核黄素代谢进行Petri网建模分析，研究结果表明：Petri网的T不变量可用于识别代谢网络中的功能模块，具备较好的生物学意义。
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| 关 键 词： | Petri网 代谢网络 复杂网络 模块化 |
| 收稿时间： | 2010-02-24 |
| 修稿时间： | 2010-6-17 |
Application of Petri net to modularization analysis of metabolic networks |
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| DING De-wu,HUANG Hai-sheng,WU Pu,WANG Ru-chuan. Application of Petri net to modularization analysis of metabolic networks[J]. Computer Engineering and Applications, 2010, 46(33): 218-220. DOI: 10.3778/j.issn.1002-8331.2010.33.062 |
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| Authors: | DING De-wu HUANG Hai-sheng WU Pu WANG Ru-chuan |
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| Affiliation: | 1.Department of Mathematics and Computer Science, Chizhou College, Chizhou, Anhui 247000, China 2.School of Computer Science and Technology,Nanjing University of Posts and Telecommunications,Nanjing 210003,China) |
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| Abstract: | Modularization analysis of metabolic networks can be helpful to understand the structure and function of these networks.However, almost all current methods consider metabolic networks as general complex networks, and resulted modules are often of biological insignificance.By applying Petri net to riboflavin metabolism network in Bacillus subtilis, the resuits suggest that T-invariant of Petri net is usable for identifying functional modules in metabolic networks, with better biological significance. |
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| Keywords: | Petri net metabolic network complex network modularization |
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