| 2，6-二吡啶基-1，4-二氢吡啶衍生物的合威 |
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| 引用本文： | 王书香,段洁,李志艳.2，6-二吡啶基-1，4-二氢吡啶衍生物的合威[J].广州化工,2010,38(3):53-54. |
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| 作者姓名： | 王书香 段洁 李志艳 |
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| 作者单位： | 河北大学化学与环境科学学院,河北,保定,071002 |
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| 基金项目： | 河北大学自然科学基金资助课题 |
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| 摘 要： | 以烟酰乙酸乙酯、醛和醋酸铵为原料，合成了一系列2，6-二吡啶基-1，4-二氢吡啶衍生物，收率为40％～88％。探讨了溶剂和底物结构对反应的影响。与在乙醇中回流反应相比，该反应在无溶剂条件下进行时，反应时间短，产物收率高。
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| 关 键 词： | 2 6-zptt啶基-1 4-二氢吡啶 无溶剂 Hantzsch缩合 |
Synthesis of 2,6-dipyridinyl-1,4-dihydropyridines |
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| WANG Shu-xiang,DUAN Jie,LI Zhi-yan.Synthesis of 2,6-dipyridinyl-1,4-dihydropyridines[J].GuangZhou Chemical Industry and Technology,2010,38(3):53-54. |
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| Authors: | WANG Shu-xiang DUAN Jie LI Zhi-yan |
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| Affiliation: | WANG Shu -xiang, DUAN Jie, LI Zhi -yah (College of Chemistry and Environmental Science, Hebei University, Hebei Baoding 071002, China) |
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| Abstract: | A rang of 2,6 - dipyridinyl - 1,4 - dihydropyridines were prepared with 40% - 88% yields condensation of ethyl nicotinoylaeetate, aldehydes and ammonium acetate, and the effects of solvent and the substrate were investigated. Under solvent -free condition, that carried out in ethanol under refluxing condition. the reaction time was shorter and the yield was through the structure of higher than |
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| Keywords: | 2 6 - dipyridinyl - 1 4 - dihydropyridines solvent - free Hantzsch reaction |
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