Bacterial pathogenesis: a variation on variation in Lyme disease |
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Authors: | M Koomey |
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Affiliation: | Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, 48109 USA. mkoomey@umich.edu |
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Abstract: | The discovery of antigenic variation in Borrelia burgdorferi, the bacterium that causes Lyme disease, provides a potential explanation for the chronic nature of infection as well as new insights into the genetic structure of highly recombinogenic loci responsible for combinatorial genetic diversification. |
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