Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores |
| |
Authors: | Julie A Conquer Bruce J Holub |
| |
Affiliation: | (1) Department of Human Biology and Nutritional Sciences, University of Guelph, N1G 2W1 Guelph, Ontario, Canada |
| |
Abstract: | The utilization of dietary docosahexaenoic acid (DHA; 22:6n−3) as a source of eicosapentaenoic acid (EPA; 20:5n−3) via retroconversion was investigated in both vegetarians and omnivores. For this purpose, an EPA-free preparation of DHA was
given as a daily supplement (1.62 g DHA) over a period of 6 wk. The dietary supplement provided for a marked increase in DHA
levels in both serum phospholipid (from 2.1 to 7.1 mol% in vegetarians and 2.2 to 7.6 mol% in omnivores) and platelet phospholipid
(from 1.1 to 3.4 mol% in vegetarians and 1.4 to 3.9 mol% in omnivores). EPA levels rose to a significant but much lesser extent,
while 20:4n−6, 22:5n−6, and 22:5n−3 all decreased. Based on the serum phospholipid data, the retroconversion of DHA to EPA
in vivo was estimated to be 9.4% overall with no significant difference between omnivores and vegetarians. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|