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Redundant pathways of sunscreen biosynthesis in a cyanobacterium |
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| Authors: | Spence Edward Dunlap Walter C Shick J Malcolm Long Paul F |
| Affiliation: | Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, UK. |
| Abstract: | Route of the sun block: according to empirical evidence, sun-screening mycosporine-like amino acids (MAAs) in Eukarya originate from the shikimic acid pathway, whereas in cyanobacteria, biosynthesis of the MAA shinorine reportedly occurs through the pentose phosphate pathway. However, gene deletion shows that the cyanobacterium Anabaena variabilis ATCC 29143 does not biosynthesise shinorine exclusively by this route. |
| Keywords: | Anabaena cyanobacteria gene deletion mycosporine‐like amino acids pentose‐phosphate pathway shikimate pathway |
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