Possible chemical basis for histocompatibility-related mating preference in mice |
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| Authors: | F. J. Schwende J. W. Jorgenson M. Novotny |
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| Affiliation: | (1) Present address: Upjohn Pharmaceuticals, 49001 Kalamazoo, Michigan;(2) Present address: Department of Chemistry, University of North Carolina, 27514 Chapel Hill, North Carolina;(3) Department of Chemistry, Indiana University, 47405 Bloomington, Indiana |
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| Abstract: | High-resolution chromatographic profiles of urinary volatiles were quantitatively recorded and statistically evaluated for the female mice genetically differing in a small region of the major histocompatibility complex on the 17th chromosome. Both immature and estrogenized animals were evaluated. While there seem to be no specific volatile products of the histocompatibility genes, statistically significant differences were readily observed with the immature females of different haplotypes, involving the general range of secondary volatile metabolites. Their possible role in olfactory communication is discussed. |
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| Keywords: | Female mice mating preference major histocompatibility complex olfactory communication capillary gas chromatography Mus musculus urine volatiles |
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