| 玉米须急性毒性及致突变性 |
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| 引用本文： | 刘静波,王翠娜,刘军,路爽,张城,蔡玥.玉米须急性毒性及致突变性[J].吉林大学学报(工学版),2011(Z2):359-363. |
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| 作者姓名： | 刘静波 王翠娜 刘军 路爽 张城 蔡玥 |
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| 作者单位： | 吉林大学军需科技学院 |
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| 基金项目： | 吉林省科技发展计划项目(20080224) |
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| 摘 要： | 考察了玉米须对小鼠急性毒性及致突变作用。利用最大耐受量法对小鼠的急性毒性进行研究,采用常用的小鼠精子畸形,骨髓微核,Ames试验考察玉米须/玉米须水提液对小鼠是否有致突变作用。结果表明,玉米须的LD50≥15g/kg,按照国家标准规定属于实际无毒物质;玉米须对抑制小鼠精子畸形有一定抑制作用,并且对小鼠雄性器官、摄食量及体重变化无影响;骨髓微核试验及Ames试验均表明玉米须无致突变作用。
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| 关 键 词： | 食品科学技术 玉米须 精子畸形 骨髓微核 Ames试验 |
Acute toxicology and mutagenic study with corn silk |
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| LIU Jing-bo,WANG Cui-na,LIU Jun,LU Shuang,ZHANG Cheng,CAI.Acute toxicology and mutagenic study with corn silk[J].Journal of Jilin University:Eng and Technol Ed,2011(Z2):359-363. |
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| Authors: | LIU Jing-bo WANG Cui-na LIU Jun LU Shuang ZHANG Cheng CAI |
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| Affiliation: | Yue(College of Quartermaster Technology,Jilin University,Changchun 130062,China) |
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| Abstract: | The acute toxicology and mutagenic action of corn silk were investigated.Acute toxicology was studied by MTD,and mutagenic action was studied by sperm abnormality test,bone marrow cell micronucleus test and Ames test.The results show that the LD50 of corn silk in higher than 15 g/kg,which indicated actual innocuous substance;Corn silk has no adverse effect on sperm form,male organs and body weight,moreover,the Ames test and bone marrow cell micronucleus test demostrate have no mutagenic action. |
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| Keywords: | food science and technology corn silk sperm abnormality bone marrow cell micronucleus Ames test |
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