Effects of Myricetin‐Containing Ethanol Solution on High‐Fat Diet Induced Obese Rats |
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| Authors: | Hsueh‐Chin Chao Pei‐Feng Tsai Sheng‐Chi Lee Yeong‐Shenn Lin Ming‐Chang Wu |
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| Affiliation: | 1. Dept. of Food Science, National Pingtung Univ. of Science and Technology, Neipu, Pingtung, Taiwan;2. Graduate Inst. of Food Science and Technology, National Taiwan Univ., Taipei City, Taiwan;3. Orthopedic Dept., Kaohsiung Veterans Hospital Pingtung Branch, Neipu Shiang, Pingtung, Taiwan;4. Dept. of Agribusiness Management, National Pingtung Univ. of Science and Technology, Neipu, Pingtung, Taiwan |
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| Abstract: | Myricetin is a natural flavonol widely occurring in wines. Many beneficial effects of myricetin in alcoholic beverages have been reported before, but never including anti‐obesity. In the present study, we fed obese male Sprague–Dawley rats with ethanol solutions containing various concentrations of myricetin and found that myricetin may maintain the food intake while reduce the weight‐gain, feed efficiency, level of blood lipids, adipocyte size, and weight and size of the perirenal and epididymal adipose tissues (P < 0.01). Our experiment data also show that the anti‐obesity effect may be associated with the upregulation of adropin and β‐endorphin levels. Based on the above‐described findings, we propose the potential for myricetin‐containing alcoholic beverages to be developed into anti‐obesity health food. |
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| Keywords: | ethanol solution high‐fat diet myricetin obesity |
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