| 烟酰胺对长波紫外线照射后人体黑素细胞中黑素小体运动与分布的影响 |
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| 引用本文： | 帕它木·莫合买提,金锡鹏,张玉彬. 烟酰胺对长波紫外线照射后人体黑素细胞中黑素小体运动与分布的影响[J]. 日用化学工业, 2007, 37(1): 65-67 |
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| 作者姓名： | 帕它木·莫合买提 金锡鹏 张玉彬 |
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| 作者单位： | 1. 新疆医科大学,公共卫生学院,劳动卫生与环境卫生学教研室,新疆,乌鲁木齐,830054
2. 复旦大学,公共卫生学院,皮肤生理毒理研究室,上海,200032 |
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| 基金项目： | 新疆维吾尔自治区科学技术厅资助项目 |
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| 摘 要： | 研究了烟酰胺对经UVA照射后人皮肤黑素细胞中黑素小体运动速率和黑素小体分布的影响。结果显示:烟酰胺对人皮肤黑素细胞中黑素小体运动速率的影响不显著;经0.2 J/cm2UVA照射后,在不同时间给予烟酰胺后,随着烟酰胺作用浓度的变化,黑素细胞中黑素小体的分布呈现明显的改变,其中烟酰胺0.25 mg/mL和1.25 mg/mL时该变化显著。实验发现:0.25 mg/mL和1.25 mg/mL的烟酰胺能调节经UVA照射后黑素细胞中黑素小体的分布;适宜浓度的烟酰胺可以添加于皮肤化妆品中用于美白和防护UVA照射。
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| 关 键 词： | 美白化妆品 烟酰胺 黑素细胞 |
| 文章编号： | 1001-1803(2007)01-0065-03 |
| 修稿时间： | 2006-08-25 |
Intervention of nicotinamide on human skin melanosome velocity and its distribution change after UVA irradiation |
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| MUHAMMAD Patam,JIN Xi-peng,ZHANG Yu-bin. Intervention of nicotinamide on human skin melanosome velocity and its distribution change after UVA irradiation[J]. China Surfactant Detergent & Cosmetics, 2007, 37(1): 65-67 |
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| Authors: | MUHAMMAD Patam JIN Xi-peng ZHANG Yu-bin |
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| Affiliation: | 1. School of Public Health, Xinjiang Medical University, Urumqi 830054, China; 2.Laboratory of Dermo- physiology and Toxicology, School of Public Health, Fudan University, Shanghai 200032, China |
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| Abstract: | The influence of nicotinamide on melanosome movement velocity and its distribution in UVA irradiated human skin melanocytes were studied.Results showed that,the effect of nicotinamide on human skin melanosome movement velocity is not significant,while the distribution of melanosome in melanocytes after UVA(365 nm) irradiation is changes significantly depending on with the different dosage of nicotinamide in melanocytes,especially at 0.25 mg/mL and 1.25 mg/mL nicotinamide.The findings obtained from the experiments showed that nicotinamide of suitable concentrations could be used as human skin whitenning agent and for UVA protection. |
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| Keywords: | whitening cosmetics nicotinamide melanocyte |
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