808 nm近红外激光辐照三种不同的离体人组织的光传输特性

采用双积分球系统和光辐射测量技术的基本原理以及运用生物组织的光学模型 ,研究了 80 8nm激光及其线偏振激光辐照人正常小肠、人正常膀胱和人膀胱癌组织的光学特性。结果表明 ,Kubelka Munk二流模型下 ,人正常膀胱组织与人膀胱癌组织对 80 8nm激光及其线偏振激光的各个光学特性参量均有非常显著的差异 (P <0 0 1)。人正常膀胱组织对 80 8nm激光及其线偏振激光的光学特性参量均有差异 ,其中吸收系数和有效衰减系数有明显差异。人膀胱癌组织对 80 8nm激光及其线偏振激光的光学特性参量均没有显著性差异 (P >0 0 5 ) ,表明人膀胱癌组织对 80 8nm线偏振激光的退偏振较大。人正常小肠组织对 80 8nm激光及其线偏振激光的光学特性参量均有显著性差异 (P <0 0 1) ,表明人正常小肠组织对 80 8nm线偏振激光的退偏振较小。在Kubelka Munk二流模型下 ,80 8nm激光及其线偏振激光辐照三种人组织的光强分布均有明显的不同

Optical Transport Characteristics of Human Tissues in Vitro at 808 nm Linearly Polarized Laser Irradiation

In this paper, a double-integrating-spheres system, basic principle of measuring technology of ray radiation, optical model of biological tissues were used to study the optical properties of human tissues. The results of measurement showed that the parameters of optical properties of human normal bladder and human bladder cancer tissue at 808 nm laser and the linearly polarized laser in Kubelka-Munk two-flux model had prominent distinction (P<0.01). The parameters of optical properties of human normal bladder tissue for 808 nm laser and the linearly polarized laser had all distinction. Absorption coefficient and effective attenuation coefficient among all parameters of optical properties of human normal bladder tissue had obviously distinction. All parameters of optical properties of human bladder cancer tissue for 808 nm laser and the linearly polarized laser had not prominent distinction(P>0.05) which showed that the depolarization of human bladder cancer tissue to 808 nm linearly polarized irradiation was very big. The parameters of optical properties of human normal small intestine tissue at 808 nm laser and the linearly polarized laser irradiation had all prominent distinction (P<0.01), which showed that the depolarization of human normal small intestine tissue to 808 nm linearly polarized irradiation was smaller. Distribution of light intensity of three kinds of human tissues at 808 nm laser and the linearly polarized laser irradiation in Kubelka-Munk two-flux model had obviously dissimilitude.