AIDS and the gastrointestinal tract

Gastrointestinal disease in AIDS most often affects three major areas: the bowel, the esophagus, and the liver. Investigation should be tailored to identify treatable causes of disease, bearing in mind that multiple infections, superinfection, and untreatable diseases are common. Clinical decisions must be made regarding both the level of investigation necessary and the best testing procedures to use. Treatment is often only symptomatic, but in some cases a specific pathogen can be targeted.