SWAN: A distributed knowledge infrastructure for Alzheimer disease research |
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| Authors: | Yong Gao June Kinoshita Elizabeth Wu Eric Miller Ryan Lee Andy Seaborne Steve Cayzer Tim Clark |
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| Affiliation: | aMassGeneral Institute for Neurodegenerative Disease, Charlestown, MA 02129, USA;bAlzheimer Research Forum1, MA, USA;cMassachusetts Institute of Technology, Cambridge, MA 02139, USA;dHewlett-Packard Laboratories, Bristol BS34 8QZ, UK;eInitiative in Innovative Computing, Harvard University, Cambridge, MA 02138, USA |
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| Abstract: | SWAN – a Semantic Web Application in Neuromedicine – is a project to develop an effective, integrated scientific knowledge infrastructure for Alzheimer Disease (AD) researchers, enabled by Semantic Web technology and deployed on Alzforum (www.alzforum.org), a scientific web community for AD research. This infrastructure may later be deployed for research communities in other neuromedical disorders. SWAN incorporates the full biomedical research knowledge lifecycle in its ontological model, including support for personal data organization, hypothesis generation, experimentation, lab data organization, and digital pre-publication collaboration. Community, laboratory, and personal digital resources may all be organized and interconnected using SWAN's common semantic framework. |
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| Keywords: | Alzheimer disease Biomedical research Knowledge lifecycle Ontology Digital resource |
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