| 微波辐射法合成对硝基苯苄醚 |
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| 引用本文： | 李丕高,刘彦利.微波辐射法合成对硝基苯苄醚[J].石油化工,2006,35(8):754-756. |
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| 作者姓名： | 李丕高 刘彦利 |
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| 作者单位： | 延安大学,化学与化工学院,陕西,延安,716000 |
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| 摘 要： | 采用微波辐射技术,以对硝基苯酚、氢氧化钠和氯化苄为原料,在N,N-二甲基甲酰胺(DMF)溶剂存在下直接合成对硝基苯苄醚;采用熔点测定和红外光谱对产物结构进行了分析和鉴定;考察了各反应物及其溶剂的摩尔比、微波辐射功率、微波辐射时间等因素对对硝基苯苄醚收率的影响。实验结果表明,微波辐射可明显促进对硝基苯苄醚的合成,在n(对硝基苯酚)∶n(氢氧化钠)∶n(氯化苄)∶n(DMF)=1∶1.2∶1.12∶10.36、微波辐射功率400 W、微波辐射时间5.0 m in的优化条件下,对硝基苯苄醚的收率可达95.5%。该方法具有反应过程和后处理简便、反应时间短、产物收率高等特点。
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| 关 键 词： | 对硝基苯苄醚 对硝基苯酚 氯化苄 N N-二甲基甲酰胺 微波 |
| 文章编号： | 1000-8144(2006)08-0754-03 |
| 修稿时间： | 2006年3月9日 |
Synthesis of 4-Nitrophenyl Benzyl Ether Under Microwave |
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| Li Pigao,Liu Yanli.Synthesis of 4-Nitrophenyl Benzyl Ether Under Microwave[J].Petrochemical Technology,2006,35(8):754-756. |
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| Authors: | Li Pigao Liu Yanli |
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| Abstract: | 4-Nitrophenyl benzyl ether was synthesized from p-nitrophenol and benzyl chloride under microwave radiation,using N,N-dimethyl formamide(DMF)as solvent.Structures of products were identified by means of micro-melting point measuring instrument and IR.Effects of ratios of reactants to solvent,microwave irradiation power,and irradiation time on reaction were studied.Microwave irradiation can obviously increase yield of 4-nitrophenyl benzyl ether.Under optimal reaction conditions:n(p-nitrophenol) ∶n(sodium hydroxide) ∶n(benzyl chloride) ∶n(DMF)1 ∶1.2 ∶1.12 ∶10.36,microwave irradiation power 400W,irradiation time 5.0min,yield of 4-nitrophenyl benzyl ether can reach 95.5%.The method is easy for operation and for separation of products. |
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| Keywords: | 4-nitrophenyl benzyl ether p-nitrophenol benzyl chloride N N-dimethyl formamide microwave |
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