全小米膳食干预对轻度高血压患者肠道菌群的影响

本文研究了全小米膳食对轻度高血压患者肠道菌群的改善作用,结果表明,经过12周的全小米膳食干预,轻度高血压受试者的肠道菌群丰度得到显著提高,而多样性指数没有显著变化.属水平上,柔韧梭菌属和乳杆菌属的相对丰度得到显著提升(P﹤0.01),说明小米可调节轻度高血压受试者某些菌属的相对丰度.另外,以乳酸盐产生菌的积累、乙酸盐和...

Effect of Whole Foxtail Millet Diet Intervention on Gut Microbiota in Patients with Mild Hypertension

The effect of whole millet diet on gut microbiota in subjects with mild hypertension was studied.The results of the study showed that after 12 weeks of whole millet diet intervention,the gut microbiota abundance of subjects with mild hypertension was significantly increased,while the diversity index did not change significantly.At the generic level,the relative abundance of Faecalibacterium and Lactobacillus increased significantly(P<0.01),indicating that foxtail millet could regulate the relative abundance of some bacteria in mild hypertension subjects.In addition,the gut microbiota imbalance state of subjects with mild hypertension,characterized by the accumulation of lactate-producing bacteria,reduction of acetate and butyrate-producing bacteria,was improved.The relative abundance of butyrate-producing bacteria increased by 20%compared with the baseline.The improvement of gut microbiota in mild hypertensive subjects provides a new ideal and direction for the mechanism study of antihypertensive effect in whole grains.