| 微生物转化法合成L-酪氨酸 |
| |
| 引用本文： | 吴敏,韦萍,周华.微生物转化法合成L-酪氨酸[J].化学世界,2002,43(9):476-478. |
| |
| 作者姓名： | 吴敏 韦萍 周华 |
| |
| 作者单位： | 1. 东南大学化学化工系,江苏,南京,210096
2. 南京工业大学制药与生命科学学院,江苏,南京,210009 |
| |
| 摘 要： | 以对羟基苯甲醛、海因、氢氧化钠为原料 ,化学合成底物对羟基苯丙酮酸。采用来自大肠杆菌的天冬氨酸转氨酶对对羟基苯丙酮酸进行生物转化 ,并对转化条件进行了初步的研究 ,最终得到L-酪氨酸 ,转化率 75 %。
|
| 关 键 词： | L-酪氨酸 对羟基苯甲醛 微生物转化法 大肠杆菌 |
| 文章编号： | 0367-6358(2002)09-0476-03 |
Study on Synthesis of L-tyrosine by Microbial Conversion |
| |
| WU Min ,WEI Ping ,ZHOU Hua.Study on Synthesis of L-tyrosine by Microbial Conversion[J].Chemical World,2002,43(9):476-478. |
| |
| Authors: | WU Min WEI Ping ZHOU Hua |
| |
| Affiliation: | WU Min 1,WEI Ping 2,ZHOU Hua 2 |
| |
| Abstract: | A microbial conversion method of synthesis of L tyrosine has been developed. The substrate p hydroxy phenylpyruvic acid was synthesized in a chemical process from p hydroxy benzaldehyde、hydantoin and sodium hydroxide. L Tyrosine was produced by means of biotransformation of p hydroxy phenylpyruvic acid in the presence of L aspartate aminotransferase from E.coli with a conversion rate of 75%. |
| |
| Keywords: | L tyrosine p hydroxy benzaldehyde microbial conversion E coli |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
